← Thiopentone

Patient counseling sheet

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AfyaIndex · counseling handout

Thiopentone

Therapeutic agent (verify pharmacological class)

Prepared 22 Sep 2026

What it is used for

Induction of general anesthesia; used alone in short surgical procedures; short term control of seizures; elevated intracranial pressure; cerebral protection in focal cerebral ischemia as observed in head injuries and status epilepticus [this protection is due to the fact that thiopentone reduces cerebral metabolic rate and blood flow]

Warnings

Use cautiously in patients with: asthma [as it causes bronchospasm]; muscular dystrophies; myotonias; severe respiratory disorders; dose is adjusted downwards in case of renal or hepatic disorders and in elderly patients.

Possible side effects

Hypotension; myocardial depression; respiratory depression; garlic-like taste during induction; erythema; pain at injection site; laryngospasm and rarely bronchospasm; anaphylaxis [rarely]; extravasations can cause tissue necrosis. The intra-arterial injection can cause arterial spasm, thrombosis, and gangrene.

Storage

Store as labelled. Keep out of reach of children.

No reviewed patient-education article is available. The fields shown are from the currently verified medicine record and unavailable fields are not inferred.

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