Busulphan
Therapeutic agent (verify pharmacological class)
What it is used for
Chronic myelogenous leukemia [CML]; myeloproliferative disorders like severe thrombocytosis and polycythemia vera; an adjunct in the treatment of myelofibrosis; a component of pretransplant conditioning regimens in patients undergoing bone marrow transplantation for non-malignant diseases.
Warnings
It must be used only under constant supervision by physicians experienced in therapy with cytotoxic agents due to its low therapeutic index; increased incidence of infections; increased incidence of hemorrhagic complications; blood counts should be performed at least once a week. C
Possible side effects
Its major side effect is haematological toxicity, which include severe leukopenia, anaemia, and severe thrombocytopenia; hyperuricaemia due to increased catabolism; uric acid nephropathy; renal stones; acute renal failure.
Storage
Store as labelled. Keep out of reach of children.
No reviewed patient-education article is available. The fields shown are from the currently verified medicine record and unavailable fields are not inferred.