Erythropoietin, Recombinant Human
Therapeutic agent (verify pharmacological class)
What it is used for
Symptomatic anaemia associated with CRF in adults and paediatrics; prevention of anaemia of prematurity in infants with a birth weight of 0.75-1.5kg and a gestational age < 34 wks; symptomatic anaemia in adult patients with non-myeloid malignancies receiving chemotherapy; increasing the yield of autologous blood from patients in a pre-donation programme.
Warnings
HB to be monitored every 2 wks until stabilized, then every 2-4wks; dose adjustments must not be made more frequently than once a month; the IV route of administration may reduce the risk for development of antibodies to the drug in comparison to SC.
Possible side effects
Hypertension; diarrhea; naso-pharyngitis; headache; URTI; coronary artery disease; septic shock; increased mortality; pure red cell aplasia; serious cardiovascular and thromboembolic events.
Storage
16 HOW SUPPLIED/STORAGE AND HANDLING PROCRIT (epoetin alfa) injection is a sterile, clear, and colorless solution available as: Preservative-free, single-dose vials (in citrate-buffered formulation) : 2,000 Units/mL (NDC 59676-302-01), 3,000 Units/mL (NDC 59676-303-01), 4,000 Units/mL (NDC 59676-304-01), or 10,000 Units/mL (NDC 59676-310-01) supplied in cartons, each carton containing six 1 mL single-dose vials. Preservative-free, single-dose vials (in citrate-buffered formulation) : 10,000 Units/mL (NDC 59676-310-02) supplied in dispensing packs (tray) containing 25 single-dose 1 mL vials. Preservative-free, single-dose vials (in phosphate-buffered formulation) : 40,000 Units/mL (NDC 59676-340-01) supplied in dispensing packs containing four 1 mL single-dose vials. Preserved, multiple-dose vials : 20,000 Units/2mL (10,000 Units/mL) (NDC 59676-312-04) supplied in dispensing packs containing four 2 mL multiple-dose vials. Preserved, multiple-dose vials : 20,000 Units/mL (NDC 59676-320-04) supplied in dispensing packs containing four 1 mL multiple-dose vials. Store at 36°F to 46°F (2°C to 8°C). Do not freeze. Do not shake. Do not use PROCRIT that has been shaken or frozen. Store PROCRIT vials in the original carton until use to protect from light.
No reviewed patient-education article is available. The fields shown are from the currently verified medicine record and unavailable fields are not inferred.