Clinical medicine profile
lidocaine hydrochloride/ cetylpyridinium chloride teething gel
Therapeutic agent (verify pharmacological class)
- Route
- See product SmPC
- Schedule
- POM
- ATC
- Not assigned
- PPB status
- registered
This profile needs source confirmation
Some sections contain general class guidance rather than medicine-specific evidence. Confirm prescribing decisions against the current SmPC and Kenya STG/EML.
Safety essentials
The information most likely to change a prescribing or dispensing decision.
Contraindications
- [From component Lidocaine [Lignocaine]] Known hypersensitivity to the amide-type local anesthetics
- patients with Adams-Stokes syndrome or with severe degrees of SA, AV, or intraventricular heart block in the absence of an artificial pacemaker.
Precautions
- [From component Lidocaine [Lignocaine]] ECG monitoring is necessary during its IV administration
- liver disease, con- gestive heart failure, marked hypoxia, severe respiratory depression, hypovolemia, or shock
- administering lidocaine to patients with sinus bradycardia or incomplete heart block for the treatment of ventricular premature contractions without prior acceleration of heart rate
- fibrillation.
Dosing matrix
Population and organ-function guidance, shown together for faster comparison.
A small amount of gel is put on a clean fingertip or cotton wool pad and rubbed gently on to baby's gums. This is repeated after 20 minutes if required.
See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.
Review renal impairment dosing; many agents need CrCl/eGFR adjustment.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Review hepatic impairment dosing; monitor LFTs if agent is hepatically cleared or hepatotoxic.
Use, effects & interactions
Indications
- Therapeutic use is agent- and indication-specific within the class (Therapeutic agent (verify pharmacological class)).
- Use according to culture results, national guidelines (Kenya STG/EML where applicable) and the current product SmPC.
- Teething pain in babies
Adverse effects
- [From component Lidocaine [Lignocaine]] Serious side effects are uncommon.
- Drowsiness
- dizziness
- disorientation
- confusion
- lightheadedness
- psychosis
- apprehension
- tinnitus
- visual disturbances including amblyopia or diplopia
- vomiting
- paraesthesia
- sensations of heat, cold, or numbness
- difficulty swallowing
Drug interactions
Open multi-drug checker ↗- Fixed-dose/multi-ingredient product.
- Clinical details partially inherited from component monographs: Lidocaine [Lignocaine].
- Confirm combination SmPC for exact dosing.
Mechanism & disposition
It has a local anesthetic action that relieves pain and soothes the gums.
Read complete mechanism
It has a local anesthetic action that relieves pain and soothes the gums. Mechanism is agent-specific. At receptor, enzyme, ion channel, transporter or microbial target level, the drug alters a physiological or pathological pathway to produce its therapeutic effect. Confirm precise molecular mechanism in current SmPC / pharmacology reference for this INN before high-stakes decisions.
Product-specific
Product-specific
See product SmPC
are product-specific. Consider food effects, protein binding, hepatic CYP/UGT
when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.
Pregnancy, lactation & diet
[lidocaine] [Lidocaine] Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist. [Aminoacridine Mouth] Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.
[lidocaine] [Lidocaine] Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data. [Aminoacridine Mouth] Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.
Brands & loaded prices
| Brand | Manufacturer | Pack | Observed price |
|---|---|---|---|
| No reviewed brand listings are linked yet. | |||
Sources & review state
Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.