INN monograph
Selenium + Vitamin ACE
Non-Standardized Fungal Allergenic Extract [EPC] · POM
Source-linked · Updated 03 Aug 2026 · Source: FDA drug label via OpenFDA/DailyMed; PubChem; Component monographs (multi-source pipeline); Local active-ingredient clinical extract
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
- Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
- Iron: avoid in iron overload.
- Potassium: severe hyperkalaemia / untreated Addison's.
Precautions
- Warnings: If symptoms persist or worsen, or if pregnant or nursing, consult a doctor.
- Keep out of reach of children.
- Do not use if cap seal is broken or missing.
Point of care
Dosing
Adult
Dosage & Administration: Turn tube upside down, twist cap to break seal & release pellets. Using clear cap, place 3 pellets to dissolve under your tongue 3 times a day or as needed. Take apart from food or drinks. To preserve purity avoid touching pellets with fingers.
Paediatric
See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.
Renal
Fat-soluble vitamins and potassium need care in advanced CKD.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic
Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.
Safety
Drug interactions
- Prefer food-first then targeted replacement.
- Document laboratory indication for high-dose therapy.
- Public health: vitamin A, iron, folate programmes per MoH guidance.
Safety
Adverse effects
- GI upset (iron, high-dose vitamin C).
- Hypercalcaemia (vitamin D excess).
- Neuropathy with B6 megadoses.
- Flushing (niacin).
Use
Indications
- Indications & Usage: Turn tube upside down, twist cap to break seal & release pellets.
- Using clear cap, place 3 pellets to dissolve under your tongue 3 times a day or as needed.
- Take apart from food or drinks.
- To preserve purity avoid touching pellets with fingers.
Pharmacology
Mode of action
Combination product.
Full mechanism text
Combination product. Component mechanism (Vitamin A): It combines with opsin, which is the red pigment in the retina to form rhodopsin [visual purple] when it is in form of retinol. Rhodopsin is necessary for visual adaptation to darkness. Retinol and retinoic acid, being other forms of Vitamin A, are essential for growth of bone, testicular and ovarian function, for embryonic development, and for regulation of growth and differentiation of epithelial tissues.
ADME
Pharmacokinetics & PD
| Onset | Days–weeks for repletion |
|---|---|
| Duration | Depends on stores and ongoing intake |
| Route | SUBLINGUAL |
| Absorption | depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared. |
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| No brands linked yet. | |||
Special populations
Pregnancy & lactation
Pregnancy
Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.
Lactation
Maternal repletion often appropriate; avoid megadoses.
Diet
Food & alcohol
- Food
- Food
Trust
Sources & disclaimer
Source: FDA drug label via OpenFDA/DailyMed; PubChem; Component monographs (multi-source pipeline); Local active-ingredient clinical extract
Clinical review date not recorded.
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.