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New search Medicine profile selenium, zinc, folic acid, vitamin E, L-arginine, L-carnitine and coenzyme Q10 Dietary supplement

Clinical medicine profile

selenium, zinc, folic acid, vitamin E, L-arginine, L-carnitine and coenzyme Q10 Dietary supplement

Non-Standardized Fungal Allergenic Extract [EPC]

POM
Evidence state Source-linked Review date not recorded
Route
SUBLINGUAL
Schedule
POM
ATC
Not assigned
PPB status
registered
Patient advice Check interactions
01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

  • Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
  • Iron: avoid in iron overload.
  • Potassium: severe hyperkalaemia / untreated Addison's.

Precautions

  • Warnings: If symptoms persist or worsen, or if pregnant or nursing, consult a doctor.
  • Keep out of reach of children.
  • Do not use if cap seal is broken or missing.
02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

Dosage & Administration: Turn tube upside down, twist cap to break seal & release pellets. Using clear cap, place 3 pellets to dissolve under your tongue 3 times a day or as needed. Take apart from food or drinks. To preserve purity avoid touching pellets with fingers.

Paediatric

See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.

Renal

Fat-soluble vitamins and potassium need care in advanced CKD.

  • CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic

Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.

03 Clinical use

Use, effects & interactions

Indications

  • Indications & Usage: Turn tube upside down, twist cap to break seal & release pellets.
  • Using clear cap, place 3 pellets to dissolve under your tongue 3 times a day or as needed.
  • Take apart from food or drinks.
  • To preserve purity avoid touching pellets with fingers.

Adverse effects

  • GI upset (iron, high-dose vitamin C).
  • Hypercalcaemia (vitamin D excess).
  • Neuropathy with B6 megadoses.
  • Flushing (niacin).
  • Prefer food-first then targeted replacement.
  • Document laboratory indication for high-dose therapy.
  • Public health: vitamin A, iron, folate programmes per MoH guidance.
04 Pharmacology

Mechanism & disposition

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.

Vitamins and minerals act as cofactors, an…Pharmacological high-dose effects differ f…
Read complete mechanism

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.

Onset

Days–weeks for repletion

Duration

Depends on stores and ongoing intake

Route

SUBLINGUAL

Absorption

depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.

Lactation

Maternal repletion often appropriate; avoid megadoses.

06 Kenya market

Brands & loaded prices

From
Median
Listings0
BrandManufacturerPackObserved price
No reviewed brand listings are linked yet.
07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; FDA drug label via OpenFDA/DailyMed; PubChem; Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Last reviewedNot recorded
EvidenceSource-linked
Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.