INN monograph
Vitamins/Minerals/4mcg folic acid
Vitamin K [EPC], Warfarin Reversal Agent [EPC], Vitamin A [EPC] · POM
Source-linked · Updated 03 Aug 2026 · Source: Local active-ingredient clinical extract; FDA drug label via OpenFDA/DailyMed; Component monographs (multi-source pipeline); Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Kenya market
Wholesale / list prices where loaded
Risk first
Contraindications
- [Vitamins] Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
- Iron: avoid in iron overload.
- Potassium: severe hyperkalaemia / untreated Addison's. [Minerals] Hypersensitivity to the active substance or excipients.
- Additional absolute contraindications are indication- and product-specific — consult SmPC. [folic acid] CONTRAINDICATIONS: Integra FTM is contraindicated in patients with known hypersensitivity to any of its ingredients
- also, all iron compounds are contraindicated in patients with hemosiderosis, hemochromatosis, or hemolytic anemias.
- Pernicious anemia is a contraindication, as folic acid may obscure its signs and symptoms.
Precautions
- [Vitamins] Treat confirmed deficiency with monitored repletion.
- Avoid megadoses without indication.
- Iron: keep away from children (overdose lethal). [Minerals] Obtain allergy and medication history.
- Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
- Use the lowest effective dose for the shortest appropriate duration.
- Monitor for expected class adverse effects. [folic acid] WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6.
- Keep this product out of reach of children.
- In case of accidental overdose, call a doctor or poison control center immediately.
- WARNING: Folic acid alone is improper therapy in the treatment for pernicious anemia and other megaloblastic anemias where Vitamin B12 is deficient.
- PRECAUTIONS: General: Anemia is a manifestation that requires appropriate investigation to determine its cause or causes.
- No single regimen fits all cases and the status of the patient observed in follow-up is the final criterion for adequacy of therapy.
- Periodic clinical and laboratory studies are considered essential.
Point of care
Dosing
Adult
DOSAGE AND ADMINISTRATION Take one (1) caplet daily or as directed by a licensed healthcare practitioner.
Paediatric
See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.
Renal
Fat-soluble vitamins and potassium need care in advanced CKD.
- CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic
Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.
Safety
Drug interactions
- Fixed-dose/multi-ingredient product.
- Clinical details partially inherited from component monographs: Vitamins, anti-oxidants, minerals, L-Glutathione, rutin, Zeaxanthin, lutein, Folic acid.
- Confirm combination SmPC for exact dosing.
Safety
Adverse effects
- Adverse Reactions: Folate: Allergic sensitizations has been reported following both oral and parenteral administration of folate.
- Adverse reactions have been reported with specific vitamins and minerals but generally at levels substantially higher than those contained herein.
- However, allergic and idiosyncratic reactions are possible at lower levels.
Use
Indications
- INDICATIONS AND USAGE Diatrol™ is indicated to provide significant amounts of essential vitamins and mineral.
- This comprehensive nutrient profile helps prevent nutritional deficiencies of these vitamins and minerals, ensuring that the specific dietary needs are met to support overall health, energy, and vitality.
- The product is specially formulated to target common vitamin and mineral gaps, thus promoting optimal health, immune function, bone strength, and metabolic balance.
- It is intended to be used under the guidance of a licensed healthcare practitioner to ensure that any potential for nutritional deficiency is addressed in a manner that supports the individual's overall health and wellbeing.
- Contraindications: This product is contraindicated in patients with known hypersensitivity to any of its ingredients.
Pharmacology
Mode of action
Combination product.
Full mechanism text
Combination product. Component mechanism (Folic acid): It acts on megaloblastic bone marrow to produce a normoblastic marrow. Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.
ADME
Pharmacokinetics & PD
| Onset | Days–weeks for repletion |
|---|---|
| Duration | Depends on stores and ongoing intake |
| Route | ORAL / IM / IV (selected) |
| Absorption | depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared. |
Kenya
Brands & prices
| Brand | Company | Pack | KES |
|---|---|---|---|
| No brands linked yet. | |||
Special populations
Pregnancy & lactation
Pregnancy
[From component Vitamins, anti-oxidants, minerals, L-Glutathione, rutin, Zeaxanthin, lutein] See FDA/DailyMed label section on pregnancy; use only if potential benefit justifies potential risk.
Lactation
Maternal repletion often appropriate; avoid megadoses.
Diet
Food & alcohol
- Food
- Food
Trust
Sources & disclaimer
Source: Local active-ingredient clinical extract; FDA drug label via OpenFDA/DailyMed; Component monographs (multi-source pipeline); Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Clinical review date not recorded.
Decision support only — not a substitute for clinical judgment, product SmPC, or Kenya STG/EML.