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New search Medicine profile Citicoline

Clinical medicine profile

Citicoline

Amino Acid [EPC]

POM
Evidence state Source-linked Review date not recorded
Route
See product SmPC
Schedule
POM
ATC
Not assigned
PPB status
registered
Patient advice Check interactions
01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

  • Hypersensitivity to the active substance or excipients.
  • Additional absolute contraindications are indication- and product-specific — consult SmPC.

Precautions

  • Warnings: Not for use on children.
  • If symptoms continue to recur, or if sleeplessness persists continuously for more than two weeks, consult a physician.
  • As with all medicines, if you are pregnant or breast feeding , consult a heatlh professional before using this product.
  • Keep out of reach of children .
  • In case of overdose, get medical or contact a Poison Control Center right away.
  • Keep out of reach of children.
02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

Directions: Adults: Hold the spray-top close to your open mouth and spray twice directly under your tongue, three times a day. Some people notice improvement within two or three weeks, others take longer.

Paediatric

See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.

Renal

Review renal impairment dosing; many agents need CrCl/eGFR adjustment.

  • CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic

Review hepatic impairment dosing; monitor LFTs if agent is hepatically cleared or hepatotoxic.

03 Clinical use

Use, effects & interactions

Indications

  • Uses: Temporarily supports the body to rebalance Human Growth Hormone (HGH) output.
  • Symptoms of imbalanced HGH may include: poor muscle/ fat balance, dry wrinkled-looking skin, low energy, sleeplessness, weak immune system.*

Adverse effects

  • Adverse reactions vary by agent.
  • Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
  • Report suspected ADRs via national pharmacovigilance channels.
  • Professional use: confirm indication, dose, duration, monitoring and patient counselling points against current Kenya STG / EML and the product SmPC.
  • Document allergy status and key interactions.
04 Pharmacology

Mechanism & disposition

A prodrug for choline and uridine.

A prodrug for choline and uridine.Mechanism is agent-specific.At receptor, enzyme, ion channel, transpor…
Read complete mechanism

A prodrug for choline and uridine. Mechanism is agent-specific. At receptor, enzyme, ion channel, transporter or microbial target level, the drug alters a physiological or pathological pathway to produce its therapeutic effect. Confirm precise molecular mechanism in current SmPC / pharmacology reference for this INN before high-stakes decisions.

Onset

Product-specific

Duration

Product-specific

Route

See product SmPC

Elimination

are product-specific. Consider food effects, protein binding, hepatic CYP/UGT

Half-life

when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.

Lactation

Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.

06 Kenya market

Brands & loaded prices

FromKES 806
MedianKES 806
Listings6
BrandManufacturerPackObserved price
COGNIMAX Not recorded 500MG TABS 20*S KES 1,946.73Daima Chemist price-list reference ↗ Source date not recorded · verify current price
COLIHENZ TABLETS LA RENON HEALTHCARE PRIVATE LIMITED Tablet Unavailable
MEMCOLIN Not recorded 500MG TABS 10*S KES 806.25Daima Chemist price-list reference ↗ Source date not recorded · verify current price
Memcolin 500 (Citicoline Tablets 500mg) Omnicals Pharma (Pvt.) Ltd. Tablet 500mg Unavailable
Memcolin Syrup (Citicoline Syrup 500mg/5ml) Omnicals Pharma (Pvt.) Ltd. Syrup 500mg Unavailable
syschol -500 Micro Labs Limited Tablet Unavailable
07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; FDA drug label via OpenFDA/DailyMed; Professional class pharmacology (Therapeutic agent (verify pharmacological class))
Last reviewedNot recorded
EvidenceSource-linked
Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.