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New search Medicine profile Aluminium hydroxide 250mg+Dimethicone 40mg+Licorice extract 4 mg+Magnesium hydroxide 250mg
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Clinical medicine profile

Aluminium hydroxide 250mg+Dimethicone 40mg+Licorice extract 4 mg+Magnesium hydroxide 250mg

Vitamin / mineral / nutritional supplement

POM
Evidence state Source-linked Review date not recorded
Route
ORAL / IM / IV (selected)
Schedule
POM
ATC
Not assigned
PPB status
registered
Patient advice Check interactions
01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

  • [Aluminium hydroxide] Hypersensitivity to the active substance or excipients.
  • Additional absolute contraindications are indication- and product-specific — consult SmPC. [Dimethicone] Hypersensitivity to the active substance or excipients.
  • Additional absolute contraindications are indication- and product-specific — consult SmPC.

Precautions

  • [Aluminium hydroxide] Obtain allergy and medication history.
  • Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
  • Use the lowest effective dose for the shortest appropriate duration.
  • Monitor for expected class adverse effects. [Dimethicone] Warnings For extenal use only.
  • When using this product avoid contact with eyes.
  • In case of eye contact, flush with water.
  • Stop use and ask a doctor if condition worsens.
  • Symptoms last more than 7days or clear up and occur again within a few days.
02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

1-2 tab(s) between meals and at bedtime.

Paediatric

Use a current weight-based paediatric reference.

Renal

Fat-soluble vitamins and potassium need care in advanced CKD.

  • CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic

Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.

03 Clinical use

Use, effects & interactions

Indications

  • Dyspepsia, hyperacidity, gastric and duodenal ulcer, gastritis
  • also for the relief of flatulence, abdominal distention, and windy colic.
  • Clinical selection for Aluminium hydroxide 250mg+Dimethicone 40mg+Licorice extract 4 mg+Magnesium hydroxide 250mg should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC.
  • Class context: Vitamin / mineral / nutritional supplement.
  • Confirm site-specific dose, duration and monitoring before prescribing.

Adverse effects

  • [Aluminium hydroxide] Adverse reactions vary by agent.
  • Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
  • Report suspected ADRs via national pharmacovigilance channels. [Dimethicone] Adverse reactions vary by agent.
  • Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
  • Report suspected ADRs via national pharmacovigilance channels.

Drug interactions

Open multi-drug checker ↗
  • Prefer food-first then targeted replacement.
  • Document laboratory indication for high-dose therapy.
  • Public health: vitamin A, iron, folate programmes per MoH guidance.
04 Pharmacology

Mechanism & disposition

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.

Vitamins and minerals act as cofactors, an…Pharmacological high-dose effects differ f…
Read complete mechanism

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.

Onset

Days–weeks for repletion

Duration

Depends on stores and ongoing intake

Route

ORAL / IM / IV (selected)

Absorption

depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

[Aluminium hydroxide] Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist. [Dimethicone] Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.

Lactation

[Aluminium hydroxide] Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data. [Dimethicone] Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.

06 Kenya market

Brands & loaded prices

From—
Median—
Listings0
BrandManufacturerPackObserved price
No reviewed brand listings are linked yet.
07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; RxNorm (NLM RxNav); PubChem; Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Last reviewedNot recorded
EvidenceSource-linked
Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.