AfyaIndex — Drug Search

01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

[Aluminium hydroxide] Hypersensitivity to the active substance or excipients.
Additional absolute contraindications are indication- and product-specific — consult SmPC.

Precautions

[Aluminium hydroxide] Obtain allergy and medication history.
Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
Use the lowest effective dose for the shortest appropriate duration.
Monitor for expected class adverse effects.

02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

Adults: 5-10mL, 20 - 60 min after meals and at bedtime when required. Children under 5 years: Maximum of 5ml TID.

Paediatric

See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.

Renal

Fat-soluble vitamins and potassium need care in advanced CKD.

CrCl 0–120: Confirm renal dosing in product SmPC / primary label.

Hepatic

Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.

03 Clinical use

Use, effects & interactions

Indications

Therapeutic use is agent- and indication-specific within the class (Vitamin / mineral / nutritional supplement).
Use according to culture results, national guidelines (Kenya STG/EML where applicable) and the current product SmPC.
Dyspepsia, heartburn, and flatulence.

Adverse effects

[Aluminium hydroxide] Adverse reactions vary by agent.
Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
Report suspected ADRs via national pharmacovigilance channels.

Drug interactions

Open multi-drug checker ↗

Prefer food-first then targeted replacement.
Document laboratory indication for high-dose therapy.
Public health: vitamin A, iron, folate programmes per MoH guidance.

04 Pharmacology

Mechanism & disposition

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.

Vitamins and minerals act as cofactors, an…Pharmacological high-dose effects differ f…

Read complete mechanism

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.

Onset

Days–weeks for repletion

Duration

Depends on stores and ongoing intake

Route

ORAL / IM / IV (selected)

Absorption

depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.

Lactation

Maternal repletion often appropriate; avoid megadoses.

06 Kenya market

Brands & loaded prices

From—

Median—

Listings0

Brand	Manufacturer	Pack	Observed price
No reviewed brand listings are linked yet.

07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; RxNorm (NLM RxNav); PubChem; Professional class pharmacology (Vitamin / mineral / nutritional supplement)

Last reviewedNot recorded

EvidenceSource-linked

Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.