AfyaIndex
Kenyan Reference & Directory
Free lookups: 1/3 Unlock Pro
Clinical reference Find a medicine
Ctrl K
Drug categories Interaction checker
1 of 3 free lookups remaining Upgrade
New search Medicine profile Aluminium Hydroxide Gel 200mg, Magnesium Hydroxide 200mg, Simeticone 25mg per Tablet
Check interactions

Clinical medicine profile

Aluminium Hydroxide Gel 200mg, Magnesium Hydroxide 200mg, Simeticone 25mg per Tablet

Vitamin / mineral / nutritional supplement

POM
Evidence state Source-linked Review date not recorded
Route
ORAL / IM / IV (selected)
Schedule
POM
ATC
Not assigned
PPB status
registered
Patient advice Check interactions
01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

  • Hypervitaminosis risk states (hypercalcaemia for vitamin D/A).
  • Iron: avoid in iron overload.
  • Potassium: severe hyperkalaemia / untreated Addison's.

Precautions

  • Treat confirmed deficiency with monitored repletion.
  • Avoid megadoses without indication.
  • Iron: keep away from children (overdose lethal).
02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

1-2 tabs QID, 20-60 mins after meals and at bedtime when required

Paediatric

See label paediatric section if present; otherwise use paediatric formulary — do not extrapolate adult doses.

Renal

Fat-soluble vitamins and potassium need care in advanced CKD.

  • CrCl 0–120: Confirm renal dosing in product SmPC / primary label.
Hepatic

Vitamin A toxicity hepatic; niacin hepatotoxicity at high dose.

03 Clinical use

Use, effects & interactions

Indications

  • Therapeutic use is agent- and indication-specific within the class (Vitamin / mineral / nutritional supplement).
  • Use according to culture results, national guidelines (Kenya STG/EML where applicable) and the current product SmPC.
  • Dyspepsia, heartburn, and flatulence

Adverse effects

  • GI upset (iron, high-dose vitamin C).
  • Hypercalcaemia (vitamin D excess).
  • Neuropathy with B6 megadoses.
  • Flushing (niacin).

Drug interactions

Open multi-drug checker ↗
  • Prefer food-first then targeted replacement.
  • Document laboratory indication for high-dose therapy.
  • Public health: vitamin A, iron, folate programmes per MoH guidance.
04 Pharmacology

Mechanism & disposition

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.

Vitamins and minerals act as cofactors, an…Pharmacological high-dose effects differ f…
Read complete mechanism

Vitamins and minerals act as cofactors, antioxidants, structural elements or hormone precursors (e.g. vitamin D endocrine axis). Pharmacological high-dose effects differ from nutritional repletion.

Onset

Days–weeks for repletion

Duration

Depends on stores and ongoing intake

Route

ORAL / IM / IV (selected)

Absorption

depends on GI integrity, food matrix and binders (e.g. calcium/iron interactions). Fat-soluble vitamins (A,D,E,K) accumulate; water-soluble generally renally cleared.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Folic acid preconception/first trimester critical. Iron/folate common in ANC. Avoid excess vitamin A.

Lactation

Maternal repletion often appropriate; avoid megadoses.

06 Kenya market

Brands & loaded prices

From—
Median—
Listings0
BrandManufacturerPackObserved price
No reviewed brand listings are linked yet.
07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; RxNorm (NLM RxNav); PubChem; Professional class pharmacology (Vitamin / mineral / nutritional supplement)
Last reviewedNot recorded
EvidenceSource-linked
Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.