AfyaIndex — Drug Search

01 Risk first

Safety essentials

The information most likely to change a prescribing or dispensing decision.

Contraindications

Hypersensitivity to the active substance or excipients.
Additional absolute contraindications are indication- and product-specific — consult SmPC.

Precautions

Obtain allergy and medication history.
Adjust for renal/hepatic impairment, pregnancy, lactation, extremes of age and interacting drugs.
Use the lowest effective dose for the shortest appropriate duration.
Monitor for expected class adverse effects.

02 Point of care

Dosing matrix

Population and organ-function guidance, shown together for faster comparison.

Adult

Orally: 30-120mg (as HCl) in 2-3 divided doses.

Paediatric

Syrup age bands.

Renal

Caution severe RI.

CrCl 0–120: See renal_dose_adjustment; confirm product SmPC.

Hepatic

Caution severe HI.

03 Clinical use

Use, effects & interactions

Indications

Respiratory disorders associated with viscid or excessive mucus.
Clinical selection for Ambroxol should follow culture results where relevant, Kenya STG/EML recommendations, and the current product SmPC.
Class context: Mucolytic.
Confirm site-specific dose, duration and monitoring before prescribing.

Adverse effects

Adverse reactions vary by agent.
Counsel on common predictable effects and serious warning symptoms (allergy, severe rash, jaundice, unusual bleeding, severe GI symptoms, neurological changes).
Report suspected ADRs via national pharmacovigilance channels.

Drug interactions

Open multi-drug checker ↗

Professional use: confirm indication, dose, duration, monitoring and patient counselling points against current Kenya STG / EML and the product SmPC.
Document allergy status and key interactions.

04 Pharmacology

Mechanism & disposition

Mechanism is agent-specific.

Mechanism is agent-specific.At receptor, enzyme, ion channel, transpor…Confirm precise molecular mechanism in cur…

Read complete mechanism

Mechanism is agent-specific. At receptor, enzyme, ion channel, transporter or microbial target level, the drug alters a physiological or pathological pathway to produce its therapeutic effect. Confirm precise molecular mechanism in current SmPC / pharmacology reference for this INN before high-stakes decisions.

Onset

Product-specific

Duration

Product-specific

Route

See product SmPC

Elimination

are product-specific. Consider food effects, protein binding, hepatic CYP/UGT

Half-life

when adjusting for organ impairment, age and drug interactions. Verify parameters in the current SmPC.

05 Special populations

Pregnancy, lactation & diet

Pregnancy

Use only if potential benefit justifies potential risk; prefer agents with better reproductive data when alternatives exist.

Lactation

Assess infant risk vs benefit of maternal therapy; prefer agents with lactation data.

06 Kenya market

Brands & loaded prices

FromKES 159

MedianKES 539

Listings3

Brand	Manufacturer	Pack	Observed price
AMBROX	DAIMA BIASHARA / Wholesale Import	SYRUP 100ML	KES 159.10Daima Chemist price-list reference ↗ Source date not recorded · verify current price
MUCOSOLVAN LIQ.	Not recorded	15MG/5ML * 100ML	KES 624.00Daima Chemist price-list reference ↗ Source date not recorded · verify current price
SEKROL	DAIMA BIASHARA / Wholesale Import	100ML(PAED)	KES 539.10Daima Chemist price-list reference ↗ Source date not recorded · verify current price

07 Provenance

Sources & review state

Primary sourceLocal active-ingredient clinical extract; Batch A alphabetical research (INN; confirm vs SmPC/local guidelines); PubChem; Professional class pharmacology (Therapeutic agent (verify pharmacological class))

Last reviewedNot recorded

EvidenceSource-linked

Open source document ↗

Decision support only. Confirm patient-specific decisions against the current product SmPC, Kenya STG/EML, and professional judgement.